Since declaration of the Queensland Children's Hospital SDA in 2008, the Office of the Coordinator General has worked closely with Brisbane City Council, the Department of Health's Lady Cilento Children's Hospital project team, other State government agencies, the adjacent schools and the local community to coordinate development in a timely manner while managing and reducing significant impacts on the precinct during construction. The Lady Cilento Children's Hospital opened to the public in November 2014.

The Coordinator-General has approved a total of 21 SDA applications for a material change of use within the Queensland Children's Hospital SDA including:

  • Lady Cilento Children's Hospital and associated energy plant
  • Children's Hospital Foundation
  • Centre for Children's Health Research
  • Mater Hospital extension for pathology services, carpark and shop
  • Ronald McDonald House South Brisbane
  • Hancock Street Carpark
  • St Laurence's College auditorium and rooftop sports field, classrooms, chapel and new sporting facilities
  • Somerville House developments including the junior school and boarding house, new library building, an early learning centre and a café.

The Coordinator-General facilitated land use rearrangements within the Queensland Children's Hospital SDA resulting in greater efficiency in the use of land and also provided for expansion of education facilities at Somerville House and St Laurence's College.